The heavy-ion programmes in the ATLAS and CMS experiments at the Large Hadron Collider aim to probe and characterise properties of the quark-gluon plasma created in relativistic Pb-Pb collisions. Smaller collision systems involving nuclei and protons are used to distinguish between initial and final-state effects. The heavy-ion experiments explored the onset of collectivity in small systems via azimuthal correlations in p-Pb collisions, energy loss of high momentum partons via measurements of photon-tagged jets, jet shapes, heavy- flavour jets, and reconstruction of heavy-flavour hadrons. Results on hot and cold nuclear effects on charmonia and bottomonia via measurements in p-Pb and Pb-Pb are also studied. Measurements of W bosons and top quark production in p-Pb collisions will be presented.